It's been three and a half years since Wetherby last faced Leeds Medics and Dentists in league action, and the Reds will be looking for a reversal of fortune against the students which saw them lose both games in to 2011/12 season.
Wetherby will be without captain Danny Warden for the visit of Leeds M&D but have selected a strong, young side in which is a highly anticipated clash between two of the most electric back lines in Yorkshire Division Three.
Leeds Medics and Dentists will be in buoyant mood after thrashing Harrogate Pythons 55-5 last weekend, their first win of the new season.
Kick off is at 3:00pm at Grange Park.
Wetherby from:
J Barnthorpe, T Bottomley, W Cayton, M Chappell, A Dus, W Dutton, T Edwards, G Gilbert, J Greenwood, E Griffiths, T Hicks, S Hoather, W Jefferson, H Kaye, J Kaye, B Mason, M Oates, C Sheridan, A Trotman, J Wheatley
Yorkshire Three Fixtures - Saturday 26th September
Baildon vs Halifax
Bramley Phoenix vs Aireborough
Goole vs Leeds Modernians
Harrogate Pythons vs Old Otliensians
Rotherham Phoenix vs Northallerton
Stocksbridge vs Thornensians
Wetherby vs Leeds Medics and Dentists